Isophit: Twenty Reps Per Week for 12 Weeks Increased Muscle Strength and Metabolism.

Isophit: Twenty Reps Per Week for 12 Weeks Increased Muscle Strength and Metabolism.

Isometric strength training has emerged as an effective method for enhancing various aspects of muscle function. A study conducted by Komi et al. at the University of Jyväskylä, Finland, utilized monozygous twin pairs to investigate the effects of isometric strength training on mechanical, electrical, and metabolic facets of muscle function.


Over a period of 12 weeks, the training subjects (TS) undertook maximal isometric knee extensions four times a week. The regimen initially consisted of five maximal isometric contractions, each lasting 3-5 seconds, with a rest period of 30 seconds between each contraction. After the initial two weeks, the program was intensified by increasing the number of contractions by one every second week. This gradual increase in workload facilitated the participants' adaptation and contributed to the observed improvements in muscle function and metabolism.


In addition to a 20% increase in isometric knee extension strength in the trained leg, an 11% increase in the untrained leg's strength was observed. The control subjects (CS) didn't show any muscle strength change. Training also resulted in improved efficiency at submaximal loads, suggesting a more economical use of the rectus femoris muscle.


Interestingly, the study also revealed a "cross-exercise" effect, where the unexercised leg of the training subjects also demonstrated strength improvement. This result implies that maximal contractions may induce enough activation in the contralateral muscle group to increase its strength slightly.


Muscle biopsies showed increased enzyme activities indicating an enhancement of the oxidative metabolism in the trained muscle. These results were consistent with earlier findings in animals subjected to strength training exercises for several weeks.


This study affirms that isometric strength training is not only beneficial for strength enhancement but also for improving muscle efficiency by 29%, potentially due to a reduction of inhibitory inputs to the active alpha-motor neurons. The training also had a surprising effect on enhancing aerobic metabolism in the muscle, hinting at its broader metabolic benefits.


The 12-week isometric strength training program showcased significant improvements in muscle strength, muscle efficiency, and metabolic activity. The specific and gradually increasing workload used in the study underscores the importance of a structured and progressive approach. These findings highlight the potential benefits and importance of including isometric exercises in one's training routine.


For more information on isometric strength training and its significant impact on functional health and performance, visit our website at or reach out to me at


Yours in Isometric Strength,


Brad Thorpe

CEO / Inventor


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